There is a lot riding on this game for both sides when they meet on Saturday (12:30 BST).
Victory for Wrexham will guarantee them a play-off spot but anything less would open the door for either Hull City or Derby County to sneak into sixth place.
Middlesbrough already know they will at least be in the play-offs but a win might be enough to pinch the second automatic promotion place depending on the results for Ipswich and Millwall.
This will be Wrexham's first home game against Middlesbrough in the Football League; the Red Dragons have won their first Football League home game against an opponent in seven of the past 10 occasions (D1 L2), most recently beating Ipswich 5-3 in February.
Middlesbrough have lost both of their previous away games against Wrexham in all competitions, both in the FA Cup in 1973-74 (1-0) and 1999-00 (2-1).
Wrexham have won their final match in each of their past four Football League seasons, their longest ever such run.
Middlesbrough have lost their final game in three of the past five Championship seasons (W1 D1), as many as their previous 14 in the second tier beforehand (W7 D4 L3).
Between 11 March and 22 April, Middlesbrough had 179 shots in eight Championship matches and scored just seven goals (4% conversion). In their last game against Watford, they had 20 shots and scored five goals (25%).
