Manchester City make four changes to the side that drew at West Ham in the league on Saturday.
And there are some surprises, with January signings Antoine Semenyo and Marc Guehi only named as substitutes.
Ruben Dias, Tijjani Reijnders, Rayan Cherki and Jeremy Doku all start, with Nico O'Reilly and Omar Marmoush the other two players dropping to the bench.
Man City XI: Donnarumma, Nunes, Khusanov, Dias, Ait-Nouri, Rodri, Reijnders, Silva, Cherki, Doku, Haaland.
Subs: Trafford, Stones, Ake, Marmoush, Kovacic, Nico, Guéhi, Savinho, O’Reilly, Semenyo, Foden, Lewis
Real Madrid make two changes to the side that beat Elche in La Liga on Saturday.
There is a start at right-back for former Liverpool man Trent Alexander-Arnold, coming in for Dani Carvajal.
Turkey international Arda Guler is also in, replacing Frenchman Eduardo Camavinga. Compatriot Kylian Mbappe is only fit enough for the bench following a knee injury.
Real Madrid XI: Courtois, Alexander-Arnold, Huijsen, Rudiger, Fran Garcia, Valverde, Tchouameni, Pitarch, Guler, Diaz, Vinicius.
Subs: Lunin, Carvejal, Alaba, Camavinga, Mbappe, Gonzalo, Carreras, Mastantuono, Diego Aguado, Cestero, Manuel Angel, Palacios.
