Brentford are bidding for three successive Premier League wins against an Arsenal side who have scored seven goals in their past two matches.
BBC Sport examines some of the key themes before their meeting at the Gtech Community Stadium.
Brentford prepare to face the league leaders knowing their home form has generally been strong this season, although their most recent defeat happens to have taken place in their last match at the Gtech Community Stadium – and against an opponent battling relegation.
Brentford's 2-0 loss at home to Nottingham Forest on 25 January is one of only two defeats on home soil in the Premier League this season and the Bees have since responded with impressive away victories at Aston Villa and Newcastle United.
Keith Andrews' side next take on the dual challenge of facing the competition's toughest team along with a quirk of statistics: since the start of last season, Brentford have only lost consecutive home league games on two occasions, the first time of which was also a 2-0 defeat to Forest followed by a loss to Arsenal.
Brentford, though, can rely on the superlative home form of their star striker. Igor Thiago has scored nine goals in his last 10 Premier League home games, including four braces. Only Manchester City forward Erling Haaland has scored more Premier League goals than Thiago so far this season.
Arsenal's attackers have rediscovered good form of their own in recent weeks, including centre forward Viktor Gyokeres, who has scored six goals in his past eight appearances in all competitions.
The Gunners' 3-0 win against Sunderland last weekend followed a 4-0 triumph at Leeds United although the former was unusual in the sense that all three of Arsenal's goals came from open play. It is only the seventh time that has happened across the entire Premier League campaign so far – and first since the 2-1 loss at Aston Villa on 6 December.
Should Manchester City defeat Fulham at home on Wednesday night Arsenal will kick off in west London with their lead at the top of the table cut to three points.
Arteta, however, has a strong record in London derbies, winning 41 of 67 at a 61% success rate – the best ratio of any Premier League manager to have taken charge of at least 20.
Meanwhile, Arsenal have lost just one of their past 20 away games against fellow London sides (W14, D5) since the start of 2022-23.
